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Antigenic Specificity | Phosphospecific AKT1/PKBalpha (pThr308) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | Size: 100 ug/200 ul |
Applications | ELISA, Western Blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The motif corresponding to the major autophosphorylation site of the human AKT1 kinase protein. This antibody does not cross react to the non-phosphorylated AKT1 or with other unrelated phosphorylated serine. Thr308 corresponds to GATMK in human, rat, mouse, chicken and canis of AKT/PKB proteins. Akt [also known as PKB (Protein kinase B) is a family of serine/threonine kinases that plays an important role in signal transduction. There are three known isoforms of Akt in mammalian cells [Akt1 (alpha), Akt2 (beta) and Akt3 (gamma)]; Akt is activated by insulin and growth and survival factors. Akt1 is phosphorylated at Thr308 and Ser473. Additionally, Akt has been referred to as an oncogene because it has increased activity in a number of tumor |
Immunogen | Antigen Preparation: A synthetic peptide containing the phospho-Thr308 motif (GATMKTFCG) of human AKT1. |
Other Names | n/a |
Gene, Accession # | [AKT1/PKBa (pT308)] |
Catalog # | MBS462006 |
Price | $285 |
Order / More Info | Phosphospecific AKT1/PKBalpha (pThr308) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |