OCT4 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-OCT4 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | OCT4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Oct-4 (POU5F1) is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells (1). A network of key factors that includes Oct-4, Nanog, and Sox2 is necessary for the maintenance of pluripotent potential, and downregulation of Oct-4 has been shown to trigger cell differentiation (2, 3). Research studies have demonstrated that Oct-4 is a useful germ cell tumor marker (4). Oct-4 exists as two splice variants, Oct-4A and Oct-4B (5). Recent studies have suggested that the Oct-4A isoform has the ability to confer and sustain pluripotency, while Oct-4B may exist in some somatic, non-pluripotent cells (6, 7). |
| Immunogen | Immunogen: Fusion protein of human OCT4 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [POU5F1; MGC22487; OCT3; OCT4; OTF3; OTF4] |
| Gene, Accession # | [OCT4], Gene ID: 5460, NCBI: NP_001272916.1, UniProt: Q01860 |
| Catalog # | MBS8527380 |
| Price | $310 |
| Order / More Info | OCT4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Looijenga, L.H. et al. (2003) Cancer Res 63, 2244-50. 2. Pesce, M. and Scholer, H.R. (2001) Stem Cells 19, 271-278. 3. Pan, G. and Thomson, J.A. (2007) Cell Res 17, 42-9. 4. Cheng, L. et al. (2007) J Pathol 211, 1-9. 5. Takeda, J. et al. (1992) Nucleic Acids Res 20, 4613-20. 6. Cauffman, G. et al. (2006) Stem Cells 24, 2685-91. 7. Lee, J. et al. (2006) J Biol Chem 281, 33554-65. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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