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Antigenic Specificity | Survivin (CT) (TIAP) (Inhibitor of Apoptosis) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP1-3. Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas1,3. |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 128 to 140 of mouse survivin protein. |
Other Names | [Mouse Survivin (C-terminal); Mouse TIAP (C-terminal); Mouse API4 (C-terminal)], [Birc5; Birc5; Api4; TIAP; AAC-11; survivin40; Api4; Iap4] |
Gene, Accession # | Gene ID: 11799, NCBI: NP_001012273.1, UniProt: O70201 |
Catalog # | MBS396025 |
Price | $405 |
Order / More Info | Survivin (CT) (TIAP) (Inhibitor of Apoptosis) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |