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Antigenic Specificity | CD68 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous CD68 proteins. CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. CD68 molecule primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. CD68 molecule is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative spl |
Immunogen | Immunogen: Synthetic Peptide |
Other Names | [Mouse CD68; CD68; Macrosialin; Gp110; CD68] |
Gene, Accession # | [CD68], Gene ID: 968, NCBI: AAB25811.1, UniProt: P34810 |
Catalog # | MBS9700356 |
Price | $130, $220, $325 |
Order / More Info | CD68 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |