Human Apolipoprotein-H (beta2GPI) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Human Apolipoprotein-H (beta2GPI) |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.5 mg |
| Concentration | APIgG concentration is mg/ml, determined by absorbance using an extinction coefficient (E1%280) of 13.4. |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is specific for beta2GPI as demonstrated by immunoelectrophoresis and ELISA. Apolipoprotein-H, also known as beta2-Glycoprotein I (beta2GPI), is a plasma glycoprotein that circulates at a concentration of 200 ug/ml (4 uM). Synthesized in the liver, beta2GPI is a single chain molecule of 48 kDa, consisting of five repeating internally disulphide-bonded structures referred to as sushi domains. Relative to other glycoproteins, beta2GPI has an unusually high content of cysteine (6.2%), proline (8.3%) and carbohydrate (19%). Almost half the circulating beta2GPI in plasma is associated with lipoproteins of all major fractions. beta2GPI has been demonstrated to bind negatively charged phospholipids, heparin and platelets. Although th |
| Immunogen | Immunogen: Human beta2GPI purified from plasma. Cross-reactivity: Mouse, Rat, Rabbit, Pig, Dog |
| Other Names | [beta2-Glycoprotein-1 (APO-H), human], [APOH; APOH; BG; B2G1; B2GP1; B2G1] |
| Gene, Accession # | Gene ID: 350, NCBI: NP_000033.2, UniProt: P02749 |
| Catalog # | MBS512024 |
| Price | $440 |
| Order / More Info | Human Apolipoprotein-H (beta2GPI) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Lee, NS, Brewer HB Jr., Osborne JC Jr.; beta2Glycoprotein I: Molecular Properties of an Unusual Apolipoprotein, Apolipoprotein H; JBC 258, pp 4765-4770, 1983.2. Schousboe I; beta2Glycoprotein I: A Plasma Inhibitor of the Contact Activation of the Intrinsic Blood Coagulation Pathway. Blood 66, pp 1 086-1091, 1985.3. Nimpf J, Bevers EM, Bomans PHH, Till U, Wurm H, Kostner GM, Zwaal RFA; Prothrombinase activity of human platelets is inhibited by beta2Glycoprotein I; Biochimica et Biophysica Acta 884, pp 142-149, 1986. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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