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Antigenic Specificity | gamma-Catenin (C-terminal) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, rat, mouse |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot, Immunoprecipitation, Immunocytochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects an 84kDa* protein corresponding to the molecular mass of gamma-Catenin on SDS-PAGE immunoblots of A431 and Hct116 src transformed cells. In addition, this antibody recognizes only gamma-Catenin in immunoprecipitations using anti-gamma-Catenin versus anti- beta -Catenin. Plakoglobin (gamma-Catenin) is a catenin family member identified as a component of desmosomes. gamma -Catenin has high homology to beta-catenin and, like beta-catenin, it can associate with the cadherins, E-cadherin and N-cadherin. One molecule of alpha-catenin and at least one molecule of beta-catenin and gamma -Catenin simultaneously bind to a single cadherin molecule. A 19-amino acid sequence of desmoglein was found to be critical for binding of gamm |
Immunogen | Immunogen: Clone was generated from a recombinant protein that includes amino acid residues in the C-terminal region of rat gamma-Catenin. This peptide sequence is highly conserved in human and mouse gamma-Catenin. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS470014 |
Price | $325 |
Order / More Info | gamma-Catenin (C-terminal) Antibody from MYBIOSOURCE INC. |
Product Specific References | • McCrea, P.D. et al. (1991) Science 254:1359.• Miravet, S. et al. (2003) Mol. Cell. Biol. 23(20) :7391. |