Caspase 12 (NT) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase 12 (NT)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunoblot
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DescriptionSpecificity: Anti-Caspase-12 (NT) [Rabbit antibody to peptide corresponding to aa 2-17 of mouse caspase-12. Recognizes human, mouse and rat caspase-12.]. This antibody recognizes human, mouse, and rat caspase-12 (approx. 53 kD). Three distinct signaling pathways lead to programmed cell death. The death receptor and mitochondrial pathways are the main pathways in which the proteases caspase-8 and caspase-9, respectively, are involved. Endoplasmic reticulum (ER) stress is the third pathway, and caspase-12 is involved. Caspase-12, localized in the ER, is activated by ER stress and mediates ER stress-induced apoptosis. Several proteins that are associated with Alzheimer's disease, including gamma -secretase, presenilin, and beta -amyloid precur
ImmunogenAntigen: Peptide corresponding to aa 2-17 at the N-terminus of mouse caspase-12.
Other Names[Caspase-12 (NT); Caspase-12 (NT)], [CASP12; Caspase-12]
Gene, Accession #Gene ID: 479458, NCBI: NP_001070704.1, UniProt: Q075B4
Catalog #MBS194043
Price$415
Order / More InfoCaspase 12 (NT) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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