APAF1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | APAF1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | During apoptosis, APAF 1 (apoptosis protease activating factor 1) binds to Cytochrome C (APAF 2), a reaction that requires dATP, and this leads to the formation of a large multimeric complex. The complex recruits pro caspase 9, and activates caspase 9 (APAF 3). Activated caspase 9 in turn cleaves and activates caspase 3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. APAF 1 is ubiquitously expressed in human tissues. |
| Immunogen | Immunogen: APAF1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human APAF1, identical to the related Rabbit sequence, and different from the related rat sequence by one amino acid, as the immunogen |
| Other Names | [Affinity Purified Rabbit APAF 1; APAF1; APAF1; APAF-1; Apoptotic protease activating factor 1; APAF 1; APAF-1; APAF 1; APAF1; APAF-1] |
| Gene, Accession # | [APAF1], Gene ID: 317, UniProt: O14727 |
| Catalog # | MBS5312640 |
| Price | $345 |
| Order / More Info | APAF1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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