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Antigenic Specificity | AKAP10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total AKAP10 protein. Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase By sim |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human AKAP10. |
Other Names | [A kinase anchor protein 10; mitochondrial [Precursor]; Protein kinase A-anchoring protein 10; PRKA10; Dual specificity A kinase-anchoring protein 2] |
Gene, Accession # | [AKAP10], Gene ID: 11216, NCBI: NP_009133.2, UniProt: O43572 |
Catalog # | MBS9410423 |
Price | $200, $255 |
Order / More Info | AKAP10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |