AKAP10 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAKAP10
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total AKAP10 protein. Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase By sim
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human AKAP10.
Other Names[A kinase anchor protein 10; mitochondrial [Precursor]; Protein kinase A-anchoring protein 10; PRKA10; Dual specificity A kinase-anchoring protein 2]
Gene, Accession #[AKAP10], Gene ID: 11216, NCBI: NP_009133.2, UniProt: O43572
Catalog #MBS9410423
Price$200, $255
Order / More InfoAKAP10 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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