cIAP-1 / HIAP-2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | cIAP-1 / HIAP-2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg |
| Concentration | 0.2 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and -7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms. |
| Immunogen | Immunogen: Synthetic peptide surrounding amino acid 530 of human cIAP-1. Positive Control: Western Blot: Jurkat cell lysate. IHC: Kidney tissue |
| Other Names | [API1; cIAP1; C-IAP1; HIAP-2; HIAP2; RNF48; MIHB; IAP2; BIRC2], [BIRC2; BIRC2; API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1; API1; IAP2; MIHB; RNF48; IAP-2; hIAP-2; hIAP2] |
| Gene, Accession # | [cIAP-1/HIAP-2], Gene ID: 329, NCBI: NP_001157.1, UniProt: Q13490 |
| Catalog # | MBS840313 |
| Price | $150, $330 |
| Order / More Info | cIAP-1 / HIAP-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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