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Antigenic Specificity | Human CD289 (N-TERMINAL) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item specifically recognises an epitope within the N-terminal (NT) region of CD289, otherwise known as Toll-like receptor 9 (TLR9), a type I transmembrane glycoprotein and member of the toll-like receptor family, which triggers MyD88 and TRAF6, resulting in NF-kappaB activation, cytokine secretion and the inflammatory response. CD289 acts as a receptor for unmethylated cytidine-phosphate-guanosine dinucleotides in bacterial DNA (CpG-DNA), playing a primary role in pathogen recognition and activation of innate immunity. This item is reported as suitable for use in immunocytochemistry on acetone fixed cells. MBS223954 specifically recognises an epitope within the N-terminal (NT) region of CD289, otherwise known as Toll-like receptor 9 (T |
Immunogen | Immunogen: Synthetic peptide SLKYNNLTVVPRNLPSSLEYLLLSYNRIVKL corresponding to amino acids 205-235 within the N-terminal domain of human CD289. Histology Positive Control Tissue: Spleen or tonsil Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human CD289 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human |
Other Names | [toll-like receptor 9; Toll-like receptor 9; toll-like receptor 9; toll-like receptor 9; CD_antigen: CD289], [TLR9; TLR9; CD289] |
Gene, Accession # | [CD289], Gene ID: 54106, NCBI: NP_059138.1, UniProt: Q9NR96 |
Catalog # | MBS223954 |
Price | $470 |
Order / More Info | Human CD289 (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |