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Antigenic Specificity | SnoN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SnoN Polyclonal Antibody detects endogenous levels of SnoN protein. Ski-like protein encoded by SKIL is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human SnoN at AA range: 590-670 |
Other Names | [Rabbit SnoN; SKIL; SNO; Ski-like protein; Ski-related oncogene; Ski-related protein] |
Gene, Accession # | [SnoN], Gene ID: 6498, NCBI: NP_001138569.1, UniProt: P12757 |
Catalog # | MBS9703146 |
Price | $130, $220, $325 |
Order / More Info | SnoN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |