Human FACTOR VIII Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human FACTOR VIII |
| Clone | [RFF-VIIIC/10] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.2 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | ELISA (EIA), Radioimmunoassays (RIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti Human Factor VIII antibody, clone RFF-VIIIC/10 recognizes human Factor VIII, an essential blood coagulation factor. Whilst circulating in the blood, it is mostly stably complexed to von Willebrand factor. It is activated through cleavage at various sites, dissociates from the complex and interacts with Factor IXa, in the presence of calcium ions and phospholipids, to convert Factor X to the activated Factor Xa, which activates thrombin. Thrombin cleaves fibrinogen into fibrin, which polymerises and cross-links to form a blood clot. The activated Factor VIII is proteolytically inactivated and cleared from the bloodstream. Defects in Factor VIII cause haemophilia A, a disorder characterised by the body's inability to control blood |
| Immunogen | Immunogen: Affinity purified human Factor VIII Buffer Solution: Phosphate buffered saline Target Species: Human |
| Other Names | [coagulation factor VIII isoform a; Coagulation factor VIII; coagulation factor VIII; antihemophilic factor; coagulation factor VIIIc; factor VIII F8B; coagulation factor VIII, procoagulant component; Antihemophilic factor; AHF; Procoagulant componentCleaved into the following 4 chains:Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain], [F8; F8; AHF; F8B; F8C; HEMA; FVIII; DXS1253E; F8C; AHF] |
| Gene, Accession # | Gene ID: 2157, NCBI: NP_000123.1, UniProt: P00451 |
| Catalog # | MBS219406 |
| Price | $430 |
| Order / More Info | Human FACTOR VIII Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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