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Antigenic Specificity | ICAM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.4mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Immunogen | Immunogen: Synthetic peptide of human ICAM1 Calculated Molecular Weight: 58kDa |
Other Names | [BB2; CD54; P3.58] |
Gene, Accession # | [ICAM1], Gene ID: 3383, NCBI: NP_000192.2 |
Catalog # | MBS2522657 |
Price | $110, $150, $225 |
Order / More Info | ICAM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |