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Antigenic Specificity | MFGE8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MFGE8 antibody detects endogenous levels of total MFGE8. Function: Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.Post-translational Modifications: Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.Sim |
Immunogen | Immunogen: A synthesized peptide derived from human MFGE8 Subcellular Location: Membrane. Secreted. Tissue Specificity: Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas. Predicted Cross Reactivity: Xenopus Similarity: Xenopus (83%) |
Other Names | [BA46; Breast epithelial antigen BA46; EDIL1; HMFG; hP47; HsT19888; Lactadherin; Medin; MFG-E8; MFGE8; MFGM; MFGM_HUMAN; Milk fat globule EGF factor 8; Milk fat globule EGF factor 8 protein; Milk fat globule-EGF factor 8; O acetyl disialoganglioside synthase; OAcGD3S; SED1; SPAG10; Sperm associated antigen 10; Sperm surface protein hP47] |
Gene, Accession # | [MFGE8], Gene ID: 4240, NCBI: NP_001108086.1, UniProt: Q08431 |
Catalog # | MBS9603042 |
Price | $240, $280 |
Order / More Info | MFGE8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |