MFGE8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMFGE8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: MFGE8 antibody detects endogenous levels of total MFGE8. Function: Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.Post-translational Modifications: Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.Sim
ImmunogenImmunogen: A synthesized peptide derived from human MFGE8 Subcellular Location: Membrane. Secreted. Tissue Specificity: Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas. Predicted Cross Reactivity: Xenopus Similarity: Xenopus (83%)
Other Names[BA46; Breast epithelial antigen BA46; EDIL1; HMFG; hP47; HsT19888; Lactadherin; Medin; MFG-E8; MFGE8; MFGM; MFGM_HUMAN; Milk fat globule EGF factor 8; Milk fat globule EGF factor 8 protein; Milk fat globule-EGF factor 8; O acetyl disialoganglioside synthase; OAcGD3S; SED1; SPAG10; Sperm associated antigen 10; Sperm surface protein hP47]
Gene, Accession #[MFGE8], Gene ID: 4240, NCBI: NP_001108086.1, UniProt: Q08431
Catalog #MBS9603042
Price$240, $280
Order / More InfoMFGE8 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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