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Antigenic Specificity | MARCO (N-term), 13-40 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry - Paraffin (IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MARCO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human MARCO. MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. |
Immunogen | n/a |
Other Names | [Macrophage receptor MARCO; Macrophage receptor with collagenous structure; Scavenger receptor class A member 2; MARCO; SCARA2] |
Gene, Accession # | [MARCO], Gene ID: 8685, NCBI: NP_006761.1, UniProt: Q9UEW3 |
Catalog # | MBS9206180 |
Price | $150, $340 |
Order / More Info | MARCO (N-term), 13-40 Antibody from MYBIOSOURCE INC. |
Product Specific References | Wright, A.K., et al. J. Leukoc. Biol. 86(3):479-489(2009) Trynka, G., et al. Gut 58(8):1078-1083(2009) Arredouani, M.S., et al. J. Immunol. 175(9):6058-6064(2005) Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005) Seta, N., et al. Arthritis Rheum. 44(4):931-939(2001) |