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Antigenic Specificity | SLC9A3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SLC9A3 antibody detects endogenous levels of total SLC9A3. Function: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient (PubMed:26358773). Plays an important role in signal transduction.Subunit Structure: Binds SLC9A3R1 and SLC9A3R2. Interacts with CHP1, CHP2 and SHANK2. Interacts with PDZK1 (via C-terminal PDZ domain) (By similarity). Interacts with PDZD3 and interactions decrease in response to elevated calcium ion levels. Interacts with AHCYL1; the interaction is required for SLC9A3 activity (PubMed:18829453, PubMed:20584908).Post-translational Modifications: Phospho |
Immunogen | Immunogen: A synthesized peptide derived from human SLC9A3 Subcellular Location: Membrane. In intestinal epithelial cells, localizes to the ileal brush border. |
Other Names | [MGC126718; MGC126720; Na(+)/H(+) exchanger 3; NHE 3; NHE-3; NHE3; SL9A3_HUMAN; SLC9A 3; Slc9a3; Sodium/hydrogen exchanger 3; Sodium/hydrogen exchanger, apical epithelial; Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3; Solute carrier family 9 (sodium/hydrogen exchanger), member 3; Solute carrier family 9 member 3] |
Gene, Accession # | [SLC9A3], Gene ID: 6550, NCBI: NP_001271280.1, UniProt: P48764 |
Catalog # | MBS9610253 |
Price | $240, $280 |
Order / More Info | SLC9A3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |