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Antigenic Specificity | DNMT3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.025 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect DNMT3a in human samples. Background: DNMT3A catalyzes the genome wide de novo methylation of CpG residues. DNA methylation on CpG residues by DNMT3A regulates gene expression and is essential for development. DNMT3A is strongly expressed in embryonic stem cells, but low in adult somatic cells. DNA methylation is coordinated with methylation of histones. DNMT3A binds to SETDB1 and HDAC1, and is involved in the repression of transcription from promoters containing an E2F binding site. |
Immunogen | Immunogen: Polyclonal antibody raised in rabbit against human DNMT3A, (DNA methyltransferase 3A), using a KLH-conjugated synthetic peptide corresponding to amino acids 92-106. Positive Control: Western blot: HEK 293 T cells, ELISA: Peptides, IP: HEK 293 T cells. |
Other Names | [DNA Methyltransferase 3a], [DNMT3A; DNMT3A; TBRS; DNMT3A2; M.HsaIIIA; Dnmt3a; DNA MTase HsaIIIA; M.HsaIIIA] |
Gene, Accession # | [DNMT3A], Gene ID: 1788, NCBI: NP_072046.2, UniProt: Q9Y6K1 |
Catalog # | MBS841019 |
Price | $345 |
Order / More Info | DNMT3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |