Mouse TIM-4 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Mouse TIM-4 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Mouse TIM-4 |
| Clone | [RMT4-54] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat anti Mouse TIM-4 antibody, clone RMT4-54 recognizes mouse Tim-4 (T-cell immunoglobulin mucin 4), a transmembrane glycoprotein and member of the immunoglobulin superfamily, exclusively expressed by antigen-presenting cells, which acts as the natural ligand of Tim-1, involved in T-cell expansion and cytokine production.Tim-4 is reported to be crucial for the phagocytosis of apoptotic cells by peritoneal macrophages, and studies have shown that interaction between Tim-1 on Th2 cells and Tim-4 on DCs, enhances Th2 cell function. The TIM-4 gene locus is associated with predisposition to asthma in both mice and humans and may be considered as a candidate disease gene for asthma. Clone RMT4-54 significantly inhibits the efficient phagocytosis |
| Immunogen | Immunogen: Tim-4-Ig, consisting of amino acids 1-288 of mouse Tim-4, coupled with the Fc portion of mouse IgG2a. Histology Positive Control Tissue: Mouse spleen Fusion Partners: Lymph node cells from immunised SD rats were fused with cells of the P3U1 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
| Other Names | [T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; TIMD-4; smuckler; spleen, mucin-containing, knockout of lymphotoxin protein; T cell immunoglobulin and mucin domain containing 4; Spleen, mucin-containing, knockout of lymphotoxin protein; SMUCKLER; T-cell immunoglobulin mucin receptor 4; TIM-4; T-cell membrane protein 4], [Timd4; Timd4; Tim4; TIM-4; B430010N18Rik; Tim4; TIMD-4; SMUCKLER; TIM-4] |
| Gene, Accession # | [TIM-4], Gene ID: 276891, NCBI: NP_848874.3, UniProt: Q6U7R4 |
| Catalog # | MBS224695 |
| Price | $300 |
| Order / More Info | Mouse TIM-4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies