PAK1 (Phospho-Ser199) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PAK1 (Phospho-Ser199) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of PAK1/2 only when phosphorylated at serine 199. The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.Brown J.L., Curr. Biol. 6:598-605(1996).Sells M.A., Curr. Biol. 7:202-210(1997).The MGC Project Team; Genome Res. 14:2121-2127(2004). |
| Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 199(T-K-S(p)-V-I) derived from Human PAK1. |
| Other Names | [ADRB2; PAK 1; P65-PAK; P68-PAK] |
| Gene, Accession # | [PAK1], Gene ID: 5058, NCBI: NP_001122092.1, UniProt: Q13153 |
| Catalog # | MBS9409407 |
| Price | $200, $255 |
| Order / More Info | PAK1 (Phospho-Ser199) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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