Edit |   |
---|---|
Antigenic Specificity | Phospho-CCR5 (Ser336) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-CCR5 (Ser336) antibody detects endogenous levels of CCR5 only when phosphorylated at Serine 336. Description: CCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120.Function: Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium |
Immunogen | Immunogen: A synthesized peptide derived from human CCR5 around the phosphorylation site of Serine 336 Subcellular Location: Cell Membrane Tissue Specificity: Highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1a and on CD4 and CD8 T-cells. Medium levels in peripheral blood leukocytes and in small intestine. Low levels in ovary and lung. Predicted Cross Reactivity: Pig, Bovine, Rabbit, Chicken Similarity: Pig (82%), Bovine (91%), Rabbit (82%), |
Other Names | [AM4 7; C C chemokine receptor type 5; C C CKR 5; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 A159A; CC Chemokine Receptor 5; CC Chemokine Receptor Type 5; CC CKR 5; CC-CKR-5; CCCKR 5; CCCKR5; CCR 5; CCR-5; CCR5; CCR5 chemokine (C C motif) receptor 5; CCR5_HUMAN; CD 195; CD195; CD195 Antigen; Chemokine C C motif receptor 5; Chemokine receptor CCR5; CHEMR13; CKR 5; CKR5; CMKBR 5; CMKBR5; FLJ78003; HIV 1 Fusion Coreceptor; HIV-1 fusion coreceptor; HIV1 fusion coreceptor; IDDM22; MIP-1 alpha receptor] |
Gene, Accession # | [CCR5], Gene ID: 1234, NCBI: NP_000570.1, UniProt: P51681 |
Catalog # | MBS9601108 |
Price | $240, $280 |
Order / More Info | Phospho-CCR5 (Ser336) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |