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Antigenic Specificity | Dnmt3b |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, chicken |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Dnmt3b Polyclonal Antibody detects endogenous levels of Dnmt3b protein. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of vari |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Dnmt3b at AA range: 1-80 |
Other Names | [Rabbit Dnmt3b; DNA (cytosine-5)-methyltransferase 3B; Dnmt3b; DNA methyltransferase HsaIIIB; DNA MTase HsaIIIB; M.HsaIIIB] |
Gene, Accession # | [DNMT3B], Gene ID: 1789, NCBI: NP_001193984.1, UniProt: Q9UBC3 |
Catalog # | MBS9700675 |
Price | $250, $250 |
Order / More Info | Dnmt3b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |