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Antigenic Specificity | RNASEH2A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1 mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid. |
Immunogen | Immunogen: Recombinant protein of human RNASEH2A |
Other Names | [AGS4; Aicardi Goutieres syndrome 4 protein; EC 3.1.26.4; JUNB; Ribonuclease HI large subunit; Ribonuclease HI subunit A; RNase H(35); RNase H2 subunit A; RNase HI large subunit; RNASEH2A; RNASEHI; RNHIA; RNHL] |
Gene, Accession # | [RNASEH2A], Gene ID: 10535, NCBI: NP_006388.2, UniProt: O75792 |
Catalog # | MBS2555587 |
Price | $150, $225, $360 |
Order / More Info | RNASEH2A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |