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Antigenic Specificity | NOD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NOD3 Antibody: NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-kappaB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells. |
Immunogen | Immunogen: NOD3 antibody was raised against an 18 amino acid synthetic peptide near the center of human NOD3. Buffer: NOD3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [NOD3; NOD3; CLR16.2; NOD3; Protein NLRC3; CARD15-like protein; NLR family, CARD domain containing 3], [NLRC3; NLRC3; NOD3; CLR16.2; NOD3; CLR16.2] |
Gene, Accession # | [NLRC3], Gene ID: 197358, NCBI: EAW85351, UniProt: Q7RTR2 |
Catalog # | MBS150315 |
Price | $375 |
Order / More Info | NOD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |