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Antigenic Specificity | JAK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Tyrosine-protein kinase JAK2(JAK2) detection. Tested with WB, IHC-P in Human. Background: Janus kinase 2, commanly called JAK2, is a human protein that has been implicated in signaling by members of the type II cytokine receptor family, the GM-CSF receptor family, the gp130 receptor family, and the single chain receptors. Exactly, JAK2 kinase is a member of a family of tyrosine kinases involved in cytokine receptor signaling. The JAK2 gene is mapped to 9p24.1. The JAK2 gene encodes a 1,132-amino acid protein that shares 95% sequence similarity to rat and pig Jak2. JAK2 is constitutively associated with the prolactin receptor and that it is activated and tyrosine phosphorylated upon PRL binding |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human JAK2 (1096-1113aa DEIYMIMTECWNNNVNQR). |
Other Names | [Tyrosine-protein kinase JAK2; Janus kinase 2; JAK 2; JAK-2; JAK2; JAK2_HUMAN; Janus Activating Kinase 2; Janus Kinase 2; JTK 10; JTK10; OTTHUMP00000043260; THCYT3; Tyrosine protein kinase JAK2; Tyrosine-protein kinase JAK2], [JAK2; JAK2; JTK10; THCYT3; JAK-2] |
Gene, Accession # | [JAK2], Gene ID: 3717, NCBI: O60674.2, UniProt: O60674 |
Catalog # | MBS175219 |
Price | $315 |
Order / More Info | JAK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |