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Antigenic Specificity | TRAF3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1, CD40 receptor-associated factor 1(CRAF1), CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes, TRAF3 promote 'Lys-63'-linked ubiquitination of target proteins. Moreover, TRAF3 undergoes both 'Lys-48'-linked and 'Lys-63'-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1, OTUB2 and OTUD5. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [AP-1; CD40bp; CRAF1; LAP1], [TRAF3; TRAF3; CAP1; LAP1; CAP-1; CRAF1; IIAE5; CD40bp; CAP1; CRAF1; CRAF1; CD40BP; LAP1] |
Gene, Accession # | [TRAF3], Gene ID: 7187, NCBI: Q13114.2, UniProt: Q13114 |
Catalog # | MBS125597 |
Price | $200, $275, $430 |
Order / More Info | TRAF3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |