INSR - middle region Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-INSR - middle region antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | INSR - middle region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | dog, guinea pig, horse, human, mouse, rat, zebrafish |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against INSR. It was validated on Western Blot using a cell lysate as a positive control.Target Description: This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). INSR can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. When present in a hybrid receptor with IGF1R, it binds IGF1.A report shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity b |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human INSR |
| Other Names | [insulin receptor isoform Long preproprotein; Insulin receptor; insulin receptor; insulin receptor] |
| Gene, Accession # | [INSR], Gene ID: 3643, NCBI: NP_000199, UniProt: P06213 |
| Catalog # | MBS3224423 |
| Price | $365 |
| Order / More Info | INSR - middle region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies