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Antigenic Specificity | Bcl10 (NT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-Bcl10 (NT) [Rabbit antibody to peptide corresponding to aa 5-19 of human Bcl10.]. This antibody recognizes human Bcl10 (31kD). Apoptosis is regulated by death domain (DD)- and/or caspase recruitment domain (CARD)-containing molecules and a caspase family of proteases. CARD-containing cell death regulators include ARC, RAIDD, Apaf-1, caspase- 9, and caspase-2. A novel CARD containing protein was recently identified and designated Bcl10, CIPER, mE10, CARMEN, and CLAP. Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene. Overexpression of Bcl10 induces JNK, p38, and NF- kappa B activation. Bcl10 interacts with caspase-9, enhances procaspase- 9 processing, and induces apoptosis through caspase-9 activation. Bcl10 |
Immunogen | Antigen: Peptide corresponding to aa 5-19 of human Bcl10. |
Other Names | [Bcl10 (NT); Bcl10 (NT)], [BCL10; BCL10; CLAP; mE10; CIPER; c-E10; CARMEN; CIPER; CLAP] |
Gene, Accession # | Gene ID: 8915, NCBI: NP_003912.1, UniProt: O95999 |
Catalog # | MBS194035 |
Price | $415 |
Order / More Info | Bcl10 (NT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |