p70 S6 Kinase Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | p70 S6 Kinase |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human p70 S6 Kinase. p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression (1,2). p70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5' oligopyrimidine tract mRNAs (1). A second isoform, p85 S6 kinase, is derived from the same gene and is identical to p70 S6 kinase except for 23 extra residues at the amino terminus, which encode a nuclear localizing signal (1). Both isoforms lie on a mitogen activated signaling pathway downstream of phosphoinositide-3 kinase (PI-3K) and the target of rapamycin, FRAP/mTOR, a pathway distinct from the Ras/MAP kinase cascade (1). The activity of p70 S6 kina |
| Immunogen | Immunogen: A synthetic -peptide of human p70 S6 Kinase |
| Other Names | [RPS6KB1; p70 S6 Kinase; p70 S6 Kinase; RPS6KB1; PS6K; S6K; S6K1; STK14A; p70(S6K)-alpha; p70-S6K; p70-alpha; Ribosomal protein S6 kinase beta-1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha;], [RPS6KB1; RPS6KB1; S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha; STK14A; S6K-beta-1; S6K1; P70S6K1; p70-S6K 1; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA] |
| Gene, Accession # | Gene ID: 6198, NCBI: NP_001258989.1, UniProt: P23443 |
| Catalog # | MBS125336 |
| Price | $200, $275, $430 |
| Order / More Info | p70 S6 Kinase Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Pullen, N. and Thomas, G. (1997) FEBS Lett. 410, 78-82. 2. Dufner, A. and Thomas, G. (1999) Exp. Cell Res. 253, 100-109. 3. Weng, Q.P. et al. (1998) J. Biol. Chem. 273, 16621-16629. 4. Pullen, N. et al. (1998) Science 279, 707-710. 5. Alessi, D.R. et al. (1998) Curr. Biol. 8, 69-81. 6. Polakiewicz, R.D. et al. (1998) J. Biol. Chem. 273, 23534-23541. 7. Fingar, D.C. et al. (2002) Genes Dev. 16, 1472-1487. 8. Saitoh, M. et al. (2002) J. Biol. Chem. 277, 20104-20112. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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