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Antigenic Specificity | AQP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AQP2 antibody is human, mouse and rat reactive. This antibody is predicted to not cross-react with other members of the aquaporin protein family. Aquaporins are membrane proteins that serve in the transfer of water and small solutes across cellular membranes. One such aquaporin, aquaporin-2 (AQP2) is located in the kidney collecting tubule and plays a critical role in water reabsorbtion (1). AQP2 is mainly localized in intracellular vesicles but upon stimulation with anti-diuretic hormone (ADH), AQP2 is translocated to the apical plasma membrane by exocytic fusion of AQP2-bearing vesicles (2). Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus (3). |
Immunogen | Immunogen: AQP2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AQP2. Buffer: AQP2 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [AQP2; AQP-CD; WCH-CD; Aquaporin-2; ADH water channel; AQP-2; aquaporin 2 (collecting duct)], [AQP2; AQP2; AQP-CD; WCH-CD; AQP-2; AQP-CD] |
Gene, Accession # | [AQP2], Gene ID: 359, NCBI: NP_000477, UniProt: P41181 |
Catalog # | MBS153508 |
Price | $375 |
Order / More Info | AQP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |