Beta-2 Microglobulin Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Beta-2 Microglobulin antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Beta-2 Microglobulin |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to human beta-2 microglobulin. beta2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on almost all cells of the body. beta-2-Microglobulin associates with the alpha heavy chain of MHC and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation. |
| Immunogen | n/a |
| Other Names | [beta-2-microglobulin; Beta-2-microglobulin; beta-2-microglobulin; beta-2-microglobulin], [B2M; B2M; IMD43] |
| Gene, Accession # | Gene ID: 567, NCBI: NP_004039.1, UniProt: P61769 |
| Catalog # | MBS857456 |
| Price | $280 |
| Order / More Info | Beta-2 Microglobulin Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Wani M.A., Haynes L.D., Kim J., Bronson C.L., Chaudhury C., Mohanty S., Waldmann T.A., Robinson J.M., Anderson C.L.; Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant beta2.microglobulin gene.; Proc. Natl. Acad. Sci. U.S.A. 1.3.5084-5089(2.06). 2. Okon M., Bray P., Vucelic D.; 1. NMR assignments and secondary structure of human beta 2.microglobulin in solution.; Biochemistry 3.8906-891.(1.92. 3. Momoi T., Suzuki M., Titani K., Hisanaga S., Ogawa H., Saito A.; Amino acid sequence of a modified beta 2.microglobulin in renal failure patient urine and long-term dialysis patient blood.; Clin. Chim. Acta 2.6:1.5-1.4(1.95). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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