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Antigenic Specificity | CHAC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.7mg/mL |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CHAC1 (ChaC, cation transport regulator homolog 1 (E. coli)) is a 264 amino acid cytoplasmic protein that belongs to the ChaC family. Induced by chemical activators of the unfolded protein response (UPR) pathway, including DTT, tunicamycin and thapsigargin, CHAC1 is a pro-apoptotic member of this pathway and may mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Overexpression of CHAC1 may lead to an increase in apoptosis, while suppression of CHAC1 results in subdued apoptosis. |
Immunogen | Immunogen: Recombinant protein of human CHAC1 |
Other Names | [cation transport regulator-like protein 1; cation transport regulator-like protein 1; ChaC, cation transport regulator homolog 1; ChaC, cation transport regulator-like 1; ChaC glutathione-specific gamma-glutamylcyclotransferase 1<] |
Gene, Accession # | [CHAC1], Gene ID: 505991, NCBI: NP_001092352.1 |
Catalog # | MBS2520019 |
Price | $110, $150, $225 |
Order / More Info | CHAC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |