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Antigenic Specificity | PAX6 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes. |
Immunogen | Immunogen: A synthesized peptide derived from human PAX6. Subcellular Localization: Nucleus. Tissue Specificity: Fetal eye, brain, spinal cord and olfactory epithelium. Isoform 5a is less abundant than the PAX6 shorter form. |
Other Names | [Paired box protein Pax-6; Aniridia type II protein; Oculorhombin; PAX6; AN2], [PAX6; PAX6; AN; AN2; FVH1; MGDA; WAGR; ASGD5; D11S812E; AN2] |
Gene, Accession # | [PAX6], Gene ID: 5080, NCBI: NP_000271.1, UniProt: P26367 |
Catalog # | MBS179233 |
Price | $160, $340, $340 |
Order / More Info | PAX6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |