Edit |   |
---|---|
Antigenic Specificity | Human CDK5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | 85 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Cdk5 (p31) peptide corresponding to the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH). Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1, MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1, p53/TP53, HDAC1, APEX1, PTK2/FAK1, huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Regulates several neuronal development and physiological processes including ne |
Immunogen | n/a |
Other Names | [CDK5 (C-Terminus) IHC-plus; CDK5; CDKN5; Cell division protein kinase 5; Crk6; Cyclin-dependent kinase 5; Protein kinase CDK5 splicing; PSSALRE; TPKII catalytic subunit; Human CDK5], [CDK5; CDK5; PSSALRE; CDKN5; TPKII catalytic subunit] |
Gene, Accession # | [CDK5], Gene ID: 1020, NCBI: NP_004926.1, UniProt: Q00535 |
Catalog # | MBS240590 |
Price | $595 |
Order / More Info | Human CDK5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |