GFRa-2 (IN) (GDNFRb) (Neurturin receptor) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GFRa-2 (IN) (GDNFRb) (Neurturin receptor) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN)1, play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNR, which is a cell surface receptor for NTN2,3. The cDNAs encoding NTNR from human, rat, chicken, and mouse have been cloned recently2-7. NTNR was also termed GDNFR, Ret ligand 2 (RETL2) or TGF- -related neurotrophic factor receptor 2 (TrnR2)4-7 and nominated as GFR -2 recently8. GFR -2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFR -2, and the Ret PTK form a complex to transduce NTN signa |
| Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 377 to 391 of human GFR -2. This sequence is identical to those of the mouse and rat. |
| Other Names | [Rabbit Glial Cell Derived Neurotrophic Factor Receptor -2 (Second Intracellular Loop); Human; Mouse; Rat], [Gfra2; Gdnfrb; Trnr2; GDNF receptor alpha-2; GDNFR-alpha-2; GFR-alpha-2; GDNFR-beta; NRTNR-alpha; NTNR-alpha] |
| Gene, Accession # | [GFRa-2], NCBI: O08842.1, UniProt: O08842 |
| Catalog # | MBS395607 |
| Price | $510 |
| Order / More Info | GFRa-2 (IN) (GDNFRb) (Neurturin receptor) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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