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Antigenic Specificity | MDM2 (pSer166) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (expected from sequence), rat (expected from sequence) |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti MDM2 (pSer166) antibody recognizes MDM2, also known as E3 ubiquitin-protein ligase Mdm2, E3 ubiquitin protein ligase, p53 E3 ubiquitin protein ligase homolog, p53-binding protein Mdm2, when phosphorylated at serine 166. MDM2 is an E3 ubiquitin-protein ligase and a member of the MDM2 protein family. MDM2 is an important negative regulator of the tumor suppressor p53. MDM2 is phosphorylated at serine 166 by Akt, leading to an increase in the E3 ubiquitin ligase activity of MDM2 (Malml?f et al. 2007). |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine 166 of human MDM2 |
Other Names | [MDM2 (pSer166)], [MDM2; MDM2; HDMX; hdm2; ACTFS; Hdm2] |
Gene, Accession # | [MDM2], Gene ID: 4193, NCBI: Q00987.1, UniProt: Q00987 |
Catalog # | MBS225284 |
Price | $375 |
Order / More Info | MDM2 (pSer166) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |