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Antigenic Specificity | CRYAA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total CRYAA antibody. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functi |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human CRYAA. |
Other Names | [CRYA1; HSPB4; CTRCT9] |
Gene, Accession # | [CRYAA], Gene ID: 1409, NCBI: NP_000385.1, UniProt: P02489 |
Catalog # | MBS9407793 |
Price | $255 |
Order / More Info | CRYAA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |