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Antigenic Specificity | PCBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. |
Immunogen | Immunogen: A synthetic peptide of human PCBP1 |
Other Names | [HEL-S-85; HNRPE1; HNRPX; hnRNP-E1; hnRNP-X] |
Gene, Accession # | [PCBP1], Gene ID: 5093, NCBI: Q15365.2, UniProt: Q15365 |
Catalog # | MBS9130944 |
Price | $200, $275, $430 |
Order / More Info | PCBP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |