Edit |   |
---|---|
Antigenic Specificity | SUPT5H - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the e |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SUPT5H |
Other Names | [transcription elongation factor SPT5 isoform a; Transcription elongation factor SPT5; transcription elongation factor SPT5; SPT5 homolog, DSIF elongation factor subunit; DRB sensitivity-inducing factor 160 kDa subunit; DSIF p160; DRB sensitivity-inducing factor large subunit; DSIF large subunit; Tat-cotransactivator 1 protein] |
Gene, Accession # | [SUPT5H], Gene ID: 6829, NCBI: NP_001104490.1, UniProt: O00267 |
Catalog # | MBS3219843 |
Price | $335 |
Order / More Info | SUPT5H - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |