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Antigenic Specificity | Glutamate Decarboxylase 65,67 (GAD 65,67) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Feline, human, mouse |
Isotype | n/a |
Format | ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes both molecular forms of rat glutamic acid decarboxylase (GAD65 and GAD67), the enzyme which converts glutamic acid to gama-aminobutyric acid (GABA), the major inhibitory transmitter in the higher brain region. Glutamic acid decarboxylase (GAD; E.C. 4.1.1.15) is the enzyme responsible for the conversion of glutamic acid to gamma-aminobutyric acid (GABA), the major inhibitory transmitter in higher brain regions, and putative paracrine hormone in pancreatic islets. Two molecular forms of GAD (65kD and 67kD, 64% aa identity between forms) are highly conserved and both forms are expressed in the CNS, pancreatic islet cells, testis, oviduct and ovary. The isoforms are regionally distributed cytoplasmically in the brains of rats and mic |
Immunogen | Immunogen: Synthetic peptide corresponding to DFLIEEIERLGQDL from the C-terminus of rat GAD. |
Other Names | [-Glutamate Decarboxylase 65,67 (GAD 65,67)], [GAD2; GAD2; GAD65; GAD65; GAD-65] |
Gene, Accession # | Gene ID: 2572, NCBI: NP_000809.1, UniProt: Q05329 |
Catalog # | MBS618215 |
Price | $830 |
Order / More Info | Glutamate Decarboxylase 65,67 (GAD 65,67) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |