LRP5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LRP5 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: LRP5 antibody detects endogenous levels of total LRP5. Description: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.Function: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling throu |
| Immunogen | Immunogen: Purified recombinant fragment of human LRP5 expressed in E. Coli Subcellular Location: Membrane. Endoplasmic Reticulum. Chaperoned to the plasma membrane by MESD. Tissue Specificity: Widely expressed, with the highest level of expression in the liver and in aorta. |
| Other Names | [BMND1; EVR1; EVR4; HBM; Low density lipoprotein receptor related protein 5; Low density lipoprotein receptor related protein 7; Low-density lipoprotein receptor-related protein 5; LR3; LRP-5; Lrp5; LRP5_HUMAN; LRP7; OPPG; OPS; OPTA1; Osteoporosis pseudoglioma syndrome; VBCH2] |
| Gene, Accession # | [LRP5], Gene ID: 4041, NCBI: NP_001278831.1, UniProt: O75197 |
| Catalog # | MBS9602699 |
| Price | $235, $295, $370 |
| Order / More Info | LRP5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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