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Antigenic Specificity | FGFR3 (Phospho-Tyr577) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FGFR3(Phospho-Tyr577) Antibody detects endogenous levels of FGFR3 only when phosphorylated at Tyr577. Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factor and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton develpment. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the innerear. Phosphorylates PLcg1, CBL. AND frs2. Ligand binding leads to the activation of severa |
Immunogen | Immunogen: A synthesized peptide derived from human FGFR3 (Phospho-Tyr577) |
Other Names | [fibroblast growth factor receptor 3 isoform 1; Fibroblast growth factor receptor 3; fibroblast growth factor receptor 3; fibroblast growth factor receptor 3; CD_antigen: CD333] |
Gene, Accession # | [FGFR3], Gene ID: 2261, NCBI: NP_000133.1, UniProt: P22607 |
Catalog # | MBS9384857 |
Price | $440, $715 |
Order / More Info | FGFR3 (Phospho-Tyr577) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |