Human IRAK1 / IRAK Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman IRAK1 / IRAK
Clone[3F7]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a,k
FormatProtein A purified
Size0.05 mg
Concentration0.5 mg/ml
ApplicationsImmunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
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DescriptionIRAK1, an IRAK type protein kinase, is a signal transducer for the immune response Toll-like receptor and interleukin-1 (IL-1) receptor signaling cascades. IRAK1 is recruited to the IL-1 receptor, phosphorylated and progressively degraded in response to IL-1 induction. The protein also has the ability to autophosphorylate. IRAK1 is immediately downstream of the MyD88 adapter protein and immediately upstream of TRAF6. IRAK1 (-/-) mice have impaired responses to interleukin-18.
ImmunogenImmunogen Description: IRAK1 (AAH54000, 530 a.a. ~ 693 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Other Names[IRAK1 / IRAK (clone 3F7) IHC-plus; IRAK1; IRAK-1; Pelle; Il1rak; IRAK; Pelle homolog; Human IRAK1; IRAK], [IRAK]
Gene, Accession #[IRAK1], Gene ID: 3654, NCBI: NP_001560.2, UniProt: P51617
Catalog #MBS246366
Price$605
Order / More InfoHuman IRAK1 / IRAK Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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