CD45RB (B-Cell Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD45RB (B-Cell Marker) |
| Clone | [BRA-11; same as BRA-11G] |
| Host Species | Mouse |
| Reactive Species | human. does not react with rat and rhesus monkey |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin. |
| Immunogen | Immunogen: Non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V) |
| Other Names | [B220, CD45R, GP180, Leukocyte common antigen (LCA), Loc, Ly-5, Lyt-4, Protein tyrosine phosphatase receptor type C (PTPRC), Receptor-type tyrosine-protein phosphatase C, T200 glycoprotein], [PTPRC; PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; CD45; L-CA] |
| Gene, Accession # | [PTPRC], Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575 |
| Catalog # | MBS438238 |
| Price | $190, $340, $340 |
| Order / More Info | CD45RB (B-Cell Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sedlak et al. Neoplasma 1989: 643, 1989. Sutherland et.al Int. Immunol., 14(8): 953 - 962 (August 1, 2002) Lim et.al Int. Immunol., 18(2):291-300 (2006 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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