CUL2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CUL2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.02 mL, 0.06 mL, 0.12 mL |
| Concentration | 2.2mg/mL |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Human CUL2 is an ortholog of nematode cul2. Michel and Xiong (1998) identified human CUL2 cDNAs and reported that the predicted protein is 745 amino acids long. Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 By similarity. The functional specificity of the ECS comple |
| Immunogen | Immunogen: Synthetic peptide of human CUL2 Calculated Molecular Weight: 87kDa |
| Other Names | [cullin-2 isoform b; Cullin-2; cullin-2; CUL-2; cullin 2] |
| Gene, Accession # | [CUL2], Gene ID: 8453, NCBI: NP_001185708.1 |
| Catalog # | MBS2522409 |
| Price | $110, $150, $225 |
| Order / More Info | CUL2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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