Urocortin-2, Human Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Urocortin-2, Human |
| Clone | 2D7 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoassay, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Monoclonal antibody 2D7 recognizes the pro-region of Urocortin-2. Urocortins 1, 2 and 3 (Ucn I, Ucn II, and Ucn III), members of the corticotropin releasing factor (CRF)4 family, have diverse bioactivities and participate in the neuroendocrine responses to stress, appetite suppression, immunomodulation, energy and water homeostasis, and cardiovascular function. Their actions are mediated through the 7-transmembrane G-protein coupled receptors CRFR1 and CRFR2. Ucn1 binds to both receptors, whereas Ucn II and Ucn III are specific to CRFR2, widely expressed in the brain, heart, vasculature, and peripheral tissues. Binding of Ucn II to its receptor triggers an intricate signaling cascade via protein kinase C, phosphatidylinositol-3-kinase/Akt a |
| Immunogen | n/a |
| Other Names | [urocortin-2 preproprotein; Urocortin-2; urocortin-2; urocortin 2; Stresscopin-related peptide; Urocortin II; Ucn II; Urocortin-related peptide], [UCN2; UCN2; UR; SRP; URP; UCNI; UCN-II; SRP; URP; Ucn II] |
| Gene, Accession # | Gene ID: 90226, NCBI: NP_149976.1, UniProt: Q96RP3 |
| Catalog # | MBS584817 |
| Price | $555 |
| Order / More Info | Urocortin-2, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Liew, O et al, His6-SUMO-eXact tag for producing human prepro-Urocortin 2 in Escherichia coli for raising monoclonal antibodies. J Immunol Method 2014, 403:37. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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