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Antigenic Specificity | APOBEC3G |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: APOBEC3G antibody will also detect the APOBEC3F isoform. The Apoliprotein B mRNA-editing, enzyme-catalytic, polypeptide-like (APOBEC) 3 is a multi-isoform member of the cytidine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates. Similar to TRIM5a which targets incoming retroviral capsids, APOBEC3 plays a major role in cellular defense against retroviral infection as at least two isoforms, APOBEC3G and to a lesser extent APOBEC3F, can be incorporated HIV-1 virions and induce hypermutation in the newly synthesized viral DNA and thus destabilize the viral genome. This innate mechanism of retroviral resistance is counteracted by the HIV-1 Vif protein by inducing the ubiquitization and degradatio |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a synthetic peptide corresponding to 15 amino acids near the amino-terminus of human APOBEC3G. |
Other Names | [DNA dC->dU-editing enzyme APOBEC-3G; DNA dC->dU-editing enzyme APOBEC-3G; DNA dC->dU-editing enzyme APOBEC-3G; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G; APOBEC-related cytidine deaminase; APOBEC-related protein; ARCD; APOBEC-related protein 9; ARP-9; CEM-15; CEM15; Deoxycytidine deaminase; A3G] |
Gene, Accession # | [APOBEC3G], Gene ID: 60489, NCBI: NP_068594 |
Catalog # | MBS9404631 |
Price | $320 |
Order / More Info | APOBEC3G Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |