GNL3L Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GNL3L |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: GNL3L antibody detects endogenous levels of total GNL3L. Function: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.Subunit Structure: Interacts with MDM2; this interaction, which occurs in the nucleoplasm, s |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus; Nucleolus. Tissue Specificity: Up-regulated during mitosis and down-regulated in the G1 phase. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog Similarity: Pig (91%), Bovine (100%), Horse (91%), Rabbit (82%), Dog (82%) |
| Other Names | [FLJ10613; Guanine nucleotide binding protein-like 3 (nucleolar)-like; novel GTPase; OTTHUMP00000023374] |
| Gene, Accession # | [GNL3L], Gene ID: 54552, NCBI: NP_001171748.1, UniProt: Q9NVN8 |
| Catalog # | MBS9605568 |
| Price | $240, $280 |
| Order / More Info | GNL3L Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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