V5 Tag Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityV5 Tag
Clone[E10]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
FormatProtein A purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Dot Blot (DB), ELISA (EIA), Immunoprecipitation (IP), Immunostaining (IS)
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DescriptionThe anti-V5 Tag Antibody blocks host interferon signaling and induces the ubiquitination and subsequent proteasome-mediated degradation of host STAT1. It acts as an adapter, linking host DDB1-Cullin 4 to STAT2/STAT1 complex. There is an absolute requirement of STAT2 in STAT1 degradation, as V binds specifically to STAT2. It may also act as a chaperone keeping the viral nucleoprotein soluble. It interacts with host IFIH1/MDA5 to block its activity in the transduction pathway which leads to the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state.
ImmunogenImmunogen: GKPIPNPLLGLDST (V5) synthetic peptide conjugated to KLH
Other Namesn/a
Gene, Accession #[V5 Tag]
Catalog #MBS395191
Price$315
Order / More InfoV5 Tag Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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