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Antigenic Specificity | ZFP36 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis (PubMed:9703499, PubMed:10330172, PubMed:10751406, PubMed:11279239, PubMed:12115244, PubMed:12748283, PubMed:15187101, PubMed:15634918, PubMed:17030620, PubMed:16702957, PubMed:20702587, PubMed:20221403, PubMed:21775632, PubMed:27193233, PubMed:23644599, PubMed:25815583). Acts as an 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery (PubMed:15687258, PubMed:23644599). Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via |
Immunogen | Immunogen: Recombinant Human mRNA decay activator protein ZFP36 protein (16-103AA) |
Other Names | [mRNA decay activator protein ZFP36; G0/G1 switch regulatory protein 24; Growth factor-inducible nuclear protein NUP475; Tristetraprolin1; ZFP36] |
Gene, Accession # | [ZFP36], Gene ID: 7538, NCBI: NP_003398.2, UniProt: P26651 |
Catalog # | MBS7107127 |
Price | $160, $235 |
Order / More Info | ZFP36 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |